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Implantation failure
We understand that recurrent implantation failure during IVF can be difficult to accept. There are many reasons why this may occur. If this happens during your cycle, your consultant will discuss additional options with you to improve your chances of success next time round.
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What is implantation failure?
Recurrent implantation failure is when you have two or more failed embryo transfers during a cycle of IVF or ICSI.
During your treatment, we will make recommendations on what will give you the best chance of success. In the event that your IVF cycle has failed, we'll work to determine why it is has failed and what can be done in the next cycle to improve your chances.
Maternal blood tests
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Clotting (thrombophilia) screen
Small clots in the blood have been identified as a possible cause for pregnancies failing to progress. In some cases, this can be treated with aspirin or heparin injections to thin the blood.
Immune screen
Increased levels of uterine natural killer cells (white cells) and autoantibodies (antibodies attacking specific organs) have also been suggested as a cause for the repeated failure of cycles.
The use of steroids and other drugs to suppress the immune system and to help a pregnancy develop are controversial as some of the drugs used in these treatments have side effects for both a mother and her developing baby. It’s important to understand these risks before deciding with your doctor whether testing or treatment is recommended.
Endometrial tests
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Endometrial tests
Embryo factors
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Implantation failure can also happen due to embryo factors. These factors do not occur at any lifestyle factors of the parent carrying the embryo.
Genetic screening
Small clots in the blood have been identified as a possible cause for pregnancies failing to progress. In some cases, this can be treated with aspirin or heparin injections to thin the blood.
Embryoscope™ (Time-lapse imaging)
Recording information by time-lapse photography allows us to assess more subtle changes seen during embryo development and identify the best embryos for transfer.
Paternal factors
Sperm DNA fragmentation
Assessing the degree of damage to sperm DNA can help identify those couples that would benefit from ICSI treatment.
You're not alone. We're here to help
We understand that seeking fertility help can be both physically and mentally demanding. If you'd like to know more about the fertility counselling we offer or you want a consultation with a TFP fertility expert, get in touch.
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Our IVF resources
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Debunking common infertility myths
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Understanding IVF success rates
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Counselling for your fertility journey
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What to eat before and after your IVF journey
Find your nearest TFP fertility clinic
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Ready to start your fertility journey? We're here for you
Speak to our patient support team for advice about your options and to book your first consultation with a fertility expert.